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Resources
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Ready-to-Use CARDENE I.V. Information/Support
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IMPORTANT NOTE: The online resources below are provided for your convenience. The Web sites are not operated by EKR, and EKR assumes no responsibility for any aspect of the sites and their content.
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General and Multiprofessional Web Resources
American Heart Association/American Stroke Association
www.americanheart.org
American Society of Hypertension, Inc.
www.ash-us.org
Society of Critical Care Medicine
www.sccm.org
Physician Web Resources
American Association of Neurological Surgeons
www.aans.org
American College of Chest Physicians
www.chestnet.org
American College of Emergency Physicians
www.acep.org
American Neurological Association
www.aneuroa.org
American Society of Anesthesiologists
www.asahq.org
Cardiothoracic Surgery Network
www.ctsnet.org
International Anesthesia Research Society
www.iars.org
Emergency Medicine Cardiac Research & Education Group (EMCREG)
www.emcreg.org
Emergency Medicine Residents’ Association
www.emra.org
Foundation for Education and Research in Neurological Emergencies (FERNE)
www.ferne.org
Society for Academic Emergency Medicine
http://www.saem.org
Society of Cardiovascular Anesthesiologists
www.scahq.org
Nurse Web Resources
American Association of Critical-Care Nurses
www.aacn.org
American Association of Neuroscience Nurses
www.aann.org
Emergency Nurses Association
www.ena.org
Pharmacist Web Resources
American College of Clinical Pharmacy
www.accp.com
American Society of Health-System Pharmacists
www.ashp.org
Important Safety Information
Close monitoring of the blood pressure is required during therapy. CARDENE I.V. is contraindicated in patients with known hypersensitivity to the drug and in patients with advanced aortic stenosis. Reduction of diastolic pressure and reduced afterload may worsen rather than improve myocardial oxygen balance. Caution is advised when administering CARDENE I.V. to patients with impaired renal or hepatic function, in combination with a beta-blocker in patients with congestive heart failure, or portal hypertension. Observe caution in patients with significant left ventricular dysfunction due to possible negative inotropic effect. CARDENE I.V. gives no protection against the dangers of abrupt beta-blocker withdrawal; beta-blocker dosage should be gradually reduced. Levels of cyclosporine should be closely monitored during therapy. The most common side effects of CARDENE I.V. are headache (14.6%), hypotension (5.6%), nausea/vomiting (4.9%), and tachycardia (3.5%). Less frequent adverse effects, in each case occurring at 1.4%, include ECG abnormalities, postural hypotension, ventricular extrasystoles, injection-site reaction, dizziness, sweating and polyuria.
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