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Contact Us
You can contact us in a variety of ways. Choose the contact point/type of information that best meets your needs.
Medical Information
Healthcare professionals and patients can request specific medical information, report adverse events, or provide feedback about Ready-to-Use CARDENE I.V. by contacting the Medical Information Department:
Phone: 877-207-5802
Mail: EKR Therapeutics, Inc.
1545 US Highway 206, 3rd Floor
Bedminster, NJ 07921
FAX: 866-457-0803
Contact a Representative
To have a local sales representative contact you:
Phone: 877-207-5802
EKR Corporate
Mail: EKR Therapeutics, Inc.
1545 US Highway 206, 3rd Floor
Bedminster, NJ 07921
Phone: 877-435-2524
Important Safety Information
Close monitoring of the blood pressure is required during therapy. CARDENE I.V. is contraindicated in patients with known hypersensitivity to the drug and in patients with advanced aortic stenosis. Reduction of diastolic pressure and reduced afterload may worsen rather than improve myocardial oxygen balance. Caution is advised when administering CARDENE I.V. to patients with impaired renal or hepatic function, in combination with a beta-blocker in patients with congestive heart failure, or portal hypertension. Observe caution in patients with significant left ventricular dysfunction due to possible negative inotropic effect. CARDENE I.V. gives no protection against the dangers of abrupt beta-blocker withdrawal; beta-blocker dosage should be gradually reduced. Levels of cyclosporine should be closely monitored during therapy. The most common side effects of CARDENE I.V. are headache (14.6%), hypotension (5.6%), nausea/vomiting (4.9%), and tachycardia (3.5%). Less frequent adverse effects, in each case occurring at 1.4%, include ECG abnormalities, postural hypotension, ventricular extrasystoles, injection-site reaction, dizziness, sweating and polyuria.
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